Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7
USERS' SCORE
Moderately Good
Based on 25 Reviews
7.9
Supplement Facts
Serving Size: 1 Lozenge
Amount Per Serving
%DV
Folate
167 mcg DFE(100 mcg folic acid)
42%
Vitamin B-12 (as Cyanocobalamin)
1 mg (1,000 mcg)
41,667%
Top Medical Research Studies
7
We explored the effects of folic acid on hair loss in zebrafish larvae after exposure to different concentrations of ethanol. This study revealed how gestational ethanol exposure can harm the development of sensory hair cells. We found that even small amounts of ethanol lead to a significant decrease in hair cell count.
When we co-treated the larvae with folic acid while still exposing them to ethanol, we noted a modest increase in the number of hair cells compared to those that only received ethanol. However, despite these benefits, the hair cell counts after folic acid treatment were still significantly lower than those of the control group that did not receive any ethanol or treatment.
Unfortunately, despite folic acid showing some protective effects, the results suggest it may not be enough on its own to fully prevent hair cell loss induced by ethanol. Thus, while folic acid can have a positive influence, its isolated impact on hair loss is not entirely clear due to concurrent ethanol exposure in this study. Therefore, we conclude that while folic acid does offer some benefit, more effective protection against hair cell loss may come from other treatments, such as retinoic acid.
When we co-treated the larvae with folic acid while still exposing them to ethanol, we noted a modest increase in the number of hair cells compared to those that only received ethanol. However, despite these benefits, the hair cell counts after folic acid treatment were still significantly lower than those of the control group that did not receive any ethanol or treatment.
Unfortunately, despite folic acid showing some protective effects, the results suggest it may not be enough on its own to fully prevent hair cell loss induced by ethanol. Thus, while folic acid can have a positive influence, its isolated impact on hair loss is not entirely clear due to concurrent ethanol exposure in this study. Therefore, we conclude that while folic acid does offer some benefit, more effective protection against hair cell loss may come from other treatments, such as retinoic acid.
Read More
7
We investigated the effects of folate within a well-structured study that examined its role in hair loss treatments. Although part of a marketed oral combination for diffuse hair loss, folate's specific impact was challenging to isolate because it was evaluated alongside other compounds.
Our research utilized a minimal growth culture system to mimic the decreased activity of human hair follicular keratinocytes. We compared these cells cultured with and without four key compounds of the treatment, including folate. Our findings indicated that while the overall combination improved cell metabolism and proliferation, we couldn't clearly assess folate's individual contribution to preventing hair loss.
Ultimately, this approach revealed that L-cystine was more prominently linked to protective effects against oxidative stress, overshadowing any potential benefits from folate alone. As a result, we conclude that folate's direct effectiveness for hair growth remains ambiguous within this specific formulation and context.
Our research utilized a minimal growth culture system to mimic the decreased activity of human hair follicular keratinocytes. We compared these cells cultured with and without four key compounds of the treatment, including folate. Our findings indicated that while the overall combination improved cell metabolism and proliferation, we couldn't clearly assess folate's individual contribution to preventing hair loss.
Ultimately, this approach revealed that L-cystine was more prominently linked to protective effects against oxidative stress, overshadowing any potential benefits from folate alone. As a result, we conclude that folate's direct effectiveness for hair growth remains ambiguous within this specific formulation and context.
Read More
Most Useful Reviews
9
Improved symptoms
6 people found this helpful
B-12 is essential! After a month of supplementation, I've noted a significant difference. Being bariatric, I suffered from severe hair loss and other symptoms, but they have greatly improved. I now have more energy, and although the taste is pleasant, the tablets can melt in heat.
Read More
7.5
Reduced hair loss
2 people found this helpful
Nice supplement! This dissolving tablet has a pleasant taste, making it easy to incorporate into my routine. Within a short period, alongside a healthy diet, I noticed it has greatly helped my hair and reduced hair loss, adding a bit more shine as well!
Read More
9
Prevents hair loss
1 people found this helpful
I am very pleased with the product. It offers excellent value for money and, most importantly, prevents hair loss, which works very well for me.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7
- All Researches
7
We investigated the effects of folate within a well-structured study that examined its role in hair loss treatments. Although part of a marketed oral combination for diffuse hair loss, folate's specific impact was challenging to isolate because it was evaluated alongside other compounds.
Our research utilized a minimal growth culture system to mimic the decreased activity of human hair follicular keratinocytes. We compared these cells cultured with and without four key compounds of the treatment, including folate. Our findings indicated that while the overall combination improved cell metabolism and proliferation, we couldn't clearly assess folate's individual contribution to preventing hair loss.
Ultimately, this approach revealed that L-cystine was more prominently linked to protective effects against oxidative stress, overshadowing any potential benefits from folate alone. As a result, we conclude that folate's direct effectiveness for hair growth remains ambiguous within this specific formulation and context.
Our research utilized a minimal growth culture system to mimic the decreased activity of human hair follicular keratinocytes. We compared these cells cultured with and without four key compounds of the treatment, including folate. Our findings indicated that while the overall combination improved cell metabolism and proliferation, we couldn't clearly assess folate's individual contribution to preventing hair loss.
Ultimately, this approach revealed that L-cystine was more prominently linked to protective effects against oxidative stress, overshadowing any potential benefits from folate alone. As a result, we conclude that folate's direct effectiveness for hair growth remains ambiguous within this specific formulation and context.
Read More
7
We explored the effects of folic acid on hair loss in zebrafish larvae after exposure to different concentrations of ethanol. This study revealed how gestational ethanol exposure can harm the development of sensory hair cells. We found that even small amounts of ethanol lead to a significant decrease in hair cell count.
When we co-treated the larvae with folic acid while still exposing them to ethanol, we noted a modest increase in the number of hair cells compared to those that only received ethanol. However, despite these benefits, the hair cell counts after folic acid treatment were still significantly lower than those of the control group that did not receive any ethanol or treatment.
Unfortunately, despite folic acid showing some protective effects, the results suggest it may not be enough on its own to fully prevent hair cell loss induced by ethanol. Thus, while folic acid can have a positive influence, its isolated impact on hair loss is not entirely clear due to concurrent ethanol exposure in this study. Therefore, we conclude that while folic acid does offer some benefit, more effective protection against hair cell loss may come from other treatments, such as retinoic acid.
When we co-treated the larvae with folic acid while still exposing them to ethanol, we noted a modest increase in the number of hair cells compared to those that only received ethanol. However, despite these benefits, the hair cell counts after folic acid treatment were still significantly lower than those of the control group that did not receive any ethanol or treatment.
Unfortunately, despite folic acid showing some protective effects, the results suggest it may not be enough on its own to fully prevent hair cell loss induced by ethanol. Thus, while folic acid can have a positive influence, its isolated impact on hair loss is not entirely clear due to concurrent ethanol exposure in this study. Therefore, we conclude that while folic acid does offer some benefit, more effective protection against hair cell loss may come from other treatments, such as retinoic acid.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 25 Reviews
7.9
- All Reviews
- Positive Reviews
- Negative Reviews
9
Improved symptoms
6 people found this helpful
B-12 is essential! After a month of supplementation, I've noted a significant difference. Being bariatric, I suffered from severe hair loss and other symptoms, but they have greatly improved. I now have more energy, and although the taste is pleasant, the tablets can melt in heat.
Read More
7.5
Reduced hair loss
2 people found this helpful
Nice supplement! This dissolving tablet has a pleasant taste, making it easy to incorporate into my routine. Within a short period, alongside a healthy diet, I noticed it has greatly helped my hair and reduced hair loss, adding a bit more shine as well!
Read More
9
Prevents hair loss
1 people found this helpful
I am very pleased with the product. It offers excellent value for money and, most importantly, prevents hair loss, which works very well for me.
Read More
9
Improved my hair
Excellent! Personally, it significantly helped with my hair loss. After using it for half a year, I noticed improvements within a month.
Read More
9
Hair loss stopped
The NOW Folic Acid brand has excellent quality and small, chewable tablets. It provides energy and improves cognitive functions. After using it, my hair loss ceased, and my skin improved. I recommend testing B12 levels first.
Read More
Frequently Asked Questions
9
Improved symptoms
6 people found this helpful
B-12 is essential! After a month of supplementation, I've noted a significant difference. Being bariatric, I suffered from severe hair loss and other symptoms, but they have greatly improved. I now have more energy, and although the taste is pleasant, the tablets can melt in heat.
6
Energy boost
10 people found this helpful
The supplement lasted three and a half months and contains excellent ingredients. I recommend it for anyone experiencing body pain and hair loss. The quality and packaging were perfect, and although it took a month to notice effects, it works wonders for my sisterās hair loss and has provided energy as well.
7.5
Reduced hair loss
After terrible hair loss, I began taking B12 vitamins for a month, and I noticed a decrease in hair loss. I will continue to buy these.
7.5
Reduced hair loss
2 people found this helpful
Nice supplement! This dissolving tablet has a pleasant taste, making it easy to incorporate into my routine. Within a short period, alongside a healthy diet, I noticed it has greatly helped my hair and reduced hair loss, adding a bit more shine as well!
9
Hair loss stopped
The NOW Folic Acid brand has excellent quality and small, chewable tablets. It provides energy and improves cognitive functions. After using it, my hair loss ceased, and my skin improved. I recommend testing B12 levels first.
9
Improved my hair
Excellent! Personally, it significantly helped with my hair loss. After using it for half a year, I noticed improvements within a month.
7.5
Excellent for immunity
This product is excellent in quality and quantity, boosting immunity while preventing hair loss and bone pain. Iāve used it twice now, and itās very effective.
9
Stops hair loss
A great nutritional supplement! It is excellent and halts hair loss while strengthening immunity. Thank you, Herb. Experience proves its effectiveness.
References
- Riegel K, Hengl T, Krischok S, Schlinzig K, Abts HF. L-Cystine-Containing Hair-Growth Formulation Supports Protection, Viability, and Proliferation of Keratinocytes. Clin Cosmet Investig Dermatol. 2020;13:499. doi:10.2147/CCID.S254720
- Rah YC, Park S, Koun S, Park HC, Choi J. InĀ vivo assay of the ethanol-induced embryonic hair cell loss and the protective role of the retinoic and folic acid in zebrafish larvae (Danio rerio). Alcohol. 2019;75:113. doi:10.1016/j.alcohol.2018.07.008
